Publication List

Pritzker Consortium Publications
Paper
Title Status
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mRNA Expression patterns and distribution of white matter neurons in dorsolateral prefrontal cortex of depressed patients differ from those in schizophrenia  M. Molnar et al. Published in Biological Psychiatry, 53 (2003): 1, 39-47; Reviewed in Archives of General Psychiatry
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DNA Microarray analysis of functionally discrete human brain regions reveals divergent transcriptional profiles   S. J. Evans et al. Published Neurobiology of Disease,14 (2003): 2, 240-250
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Gender specific gene expression in postmortem human brain:  localization to sex chromosomeM. P. Vawter et al. Published in Neuropsychopharmacology , 29 (2004): 2, 373-384
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Microarray Technology: a review of new strategies to discover candidate vulnerability genes in psychiatric disorders  W. E. Bunney et al. Published in American Journal of Psychiatry, 160(2003):4, 657-666
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Evaluation of sensitivity, performance and reproducibility of microarray technology in neuronal tissue  S. J. Evans, S. J. Watson, H. Akil Published in Journal of Integrative and Comparative Biology 2003
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Effect of agonal and postmortem factors on microarray expression profile:  Quality control methods in microarray analyses of postmortem human brain  H.Tomita, et al. Published Biological Psychiatry, 55(2003): 4, 346-352
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Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions J. Li, et al. Published in Human Molecular Genetics, 13(2004):6,609-616
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Untangling genetic networks of panic, phobia, fear and anxiety S. Villafuerte and M. Baumeister Published in Genome Biology, 4(2003):8, 224.1-4
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Dysregulation of the FGF system in major depression, S. J. Evans, et al. Published in PNAS, 101(2004): 43, 15506-15511
Access Paper Genome Scan and Haplotype Analyses Suggest Chromosome 5p13 as a Susceptibility Locus for Schizophrenia and Schizoaffective Disorder in a Costa Rican Pedigree, K. Cooper-Casey et al. Published in Molecular Psychiatry, Advance online publication (2005): 1-6
Access Paper Robust and Tissue-Specific Expression of TPH2 versus TPH1 in Rat Raphe and Pineal Gland, P. Patel, et al. Published in Biological Psychiatry , 55 (2003): 4, 428-433
Access Paper GeneInfoMiner--a web server for exploring biomedical literature using batch sequence ID, W. Xuan, et al. Published in Bioinformatics, 21:16 (2005) 3452-3453
Access Paper Altered cortical glutamatergic and GABAergic signal transmission with glial involvement in depression, P.V. Choudary, et al. Published in PNAS, 102 (2005) 15653-15658
Access Paper Genetical genomics: combining genetics with gene expression analysis Jun Li and Margit Burmeister Published in Human Molecular Genetics, 14:S2 (2005) R163-R169
Access Paper A Database-Linked Diagram Editor for Biological Concepts B. Yu, et al. Published in METMBS, (2005)
Access Paper Screening Potential Alllelle-Frequency Disequilibrium in Data from Affymetrix Gene Expression Arrays M. Dai et al. Published in Advances in Bioinformatics and its Applications Series in Mathematical Biology and Medicine, vol 8 (2005)
Access Paper Exploring Important Issues in the Implementation of Gene Set Enrichment Analysis Y. Wang, et al.
Access Paper Gene Definition in Different Databases and Its Implication in Microarray Data Interpretation P. Wang et al.
Access Paper Application of microarray technology in primate behavioral neuroscience research Karssen et al. Published in Methods, 38(2006):3, 227-234
Access Paper The Fibroblast Growth Factor System and Mood Disorders Turner et al. Published in Biological Psychiatry, (2006): In Press
Access Paper Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders Vawter et al. Published in Molecular Psychiatry, (2006): April 25
Access Paper SNPs on Chips: The Hidden Genetic Code in Expression Arrayss Sliwerska et al. Published in Biol Psychiatry, 61:1(2007): Jan 1
Access Paper Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data Dai et al. Published in Nucl. Acids Res., 33:20(2005): Nov. 10
Access Paper Rostral Elements of Sympatho-motor Circuitry: A Virally Mediated Transsynaptic Tracing Study Kerman et al. Published in J. Neurosci., 26:13(2006): March 29
Access Paper Tagging Sentence Boundaries in Biomedical Literature Xuan et al. Published in Lecture Note in Comp. Sci., (2007): Feb
Access Paper Supercomputing with Toys: harnessing the power of NVIDIA 8800GTX and Play Station 3 for bioinformatics problems Wilson et al. Published in Computational Systems Bioinformatics, (2007)
Access Paper An Active Visual Search Interface for Medline Xuan et al. In Press in Computational Systems Bioinformatics, (2007)
Access Paper Interactive Medline Search Engine Utilizing Biomedical Concepts and Data Integration Xuan et al. Published in BioLink (2007)
Access Paper Web-Based GeneChip Analysis System for Large-Scale Collaborative Projects Dai et al. Published in Bioinformatics, (2007)
Access Paper Methodological considerations for gene expression profiling of human brain Atz et al. Published in J Neurosci Methods, 163:2(2007)
Access Paper Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice Rozeboom et al. Published in Proc Natl Acad Sci USA(2007)
Access Paper Analysis of 5-HT6 and 5-HT7 receptor gene expression in rats showing differences in novelty-seeking behavior Ballaz et al. Published in Neuroscience, 147:2(2007)
Access Paper The 5-HT7 receptor: Role in novel object discrimination and relation to novelty-seeking behavior Ballaz et al. Published in Neuroscience, 149:1(2007)
Access Paper Stress-induced changes in primate prefrontal profiles of gene expression Karssen et al. Published in Molecular Psychiatry, 12(2007)

Pritzker Network Publications:
Paper
Title Status
Access Paper The Neuropsychological Profile of Psychotic Major Depression and its Relation to Cortisol Gomez et al. Published in Biological Psychiatry, 60(2006)
Access Paper Cortisol Circadian Rhythm Alterations in Psychotic Major Depression Keller et al.
Access Paper BDNF Val66Met Allele Is Associated with Reduced Hippocampal Volume in Healthy Subjects Bueller et al. Published in Biological Psychiatry, 59(2006):9, 812-815
Access Paper Preliminary Evidence that Hippocampal Volumes in Monkeys Predict Stress Levels of Adrenocorticotropic Hormone Lyons et al . Published in Biological Psychiatry, (2007)

Presentations, Abstracts & Posters
Paper
Description
Meeting/Date
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A) Molecules and pathways of emotion:  How individuals differ, H.Akil
Society for Neuroscience 11/10-15/01
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B) Gender differences in gene expression in human brain using microarray and model based analysis, M.P. Vawter, et al
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C) Analysis of sex differences in human cortical tissue using oligonucleotide microarrays, S. J. Evans, et al.
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A) Gene expression in neuropsychiatric disorders and controls, M. P. Vawter et al.
Amer. Coll. of Neuropsycho-pharmacology 2001
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B) Searching for the neural bases of emotional responsiveness with the aid of microarray technology S. J. Evans, et al.
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A)  Analysis of gene expression in mood disorders by different algorithms using Affymetrix microarrays, M. P. Vawter et al.
Society for Neuroscience 11/2-7/02
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B)  Transcript profiling shows selectivity of anatomical regions and physiological pathways affected in the brains of patients with mood disorders, P. V. Choudary et al.
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C)  DNA microarray analysis of dorsal lateral prefrontal cortex from patients with major depressive disorder reveals coordinated alteration of gene expression in a growth factor pathway, S. J. Evans, et al.
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D)  Analysis of gene expression in bipolar disorder reveals dysregulated signaling pathways, H. Tomita et al.
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Quantitative RT-PCR analysis of gene expression alterations in selective brain regions of patients with mood disorders, J. Li et al.
ASHG Meeting 6/13/02
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A)  Anterior cingulate gene expression differences found in bipolar disorder by oligonucleotide microarray analysis, M. P. Vawter et al.
Amer. Coll. of Neuropsycho-pharmacology 2002
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C)  Microarray studies in mood disorders:  distinct patterns seen between major depression and bipolar disorder in two frontal cortical regions, H. Akil et al.
Presentations as part of a study group:
1) Mood disorders and their treatment: Application of microarray technology, W. E. Bunney
2) Powers and problems of microarrays, S. J. Evans and S. Watson
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A)  Microarray studies in mood disorders:  distinct patterns seen between major depression and bipolar disorder in two frontal cortical regions, H. Akil et al.
Society of Biological Psychiatry 2002
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B)  Gene expression profile in anterior cingulate of bipolar disorder, M. P. Vawter et al.
Download Paper A) Mood Disorders:  The Search for Candidate Genes and Pathways, W.E. Bunney
Winter Conf on Brain Research 1/25-2/2/03
B) Microarray Technology in Major Depressive and Bipolar Disorders, J. Lopez
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Integrating Gene Annotation into Genome-Wide Expression Data Analysis, J. Li
Pacific Symposium of Biocomputing 1/3-7/03
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A) Microarrays and Brain Research:  Powers and Limitations, S. Evans, H. Akil, S. Watston
Society for Integrative and Comparative Biology 1/3-8/03
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B) Integrating Gene Annotation into Genome-Wide Expression Data Analysis, J. Li et al.
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Global Gene Expression Profiling of Postmortem Brains from Psychiatric Patients Reveals Differences in Several Psychological Pathways Between Different Mood Disorders, P.V. Choudary, et al.
XIX Int'l Congress of Genetics 7/6-11/03
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A)  Detection of Regional Differences in Protein Expression in Human Brain Tissue Using Antibody Microarrays, C. A. Caamano, et al.  
Society for Neuroscience November 8-12, 2003
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B)  Comparison of Gene Expression Profiles between Bipolar Disorder, Major Depression and Schizophrenia in Cortical Brain Regions, S.Evans, et al.
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C)  Gene Expression Profile in the Frontal Cortex of Rats Subjected to Chronic Unpredictable Stress and Antidepressant Administration:  A Comparison with Human Post Mortem Studies, J. Lopez, et al.
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D)  Dorsal Lateral Prefrontal Cortex  and Dorsal Median Thalamus in Schizophrenic Brains Show Both Common and Unique Physiological Pathway Perturbations, P.V. Choudary, et al.
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E)  Identification of Differentially Expressed Genes in Two Cortical Regions of Patients with Mood Disorders by Serial Analysis of Gene Expression (SAGE), J. Li
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F)  Identification of Genes Regulated by Multiple Antidepressants in Rat Hippocampus R.. Thompson et al.
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G)  Social Stress-related Changes in White Matter Connectivity, D. Lyons et al.
H)  Cortical Regions in Schizophrenia Show Overlapping Expression Patterns, M. Vawter et al.
Download Paper I)  Gene Expression Profiles in Post Mortem Brain of Mood Disorder Patients, H. Tomita, et al.
Download Paper J) Tbr1 mRNA Expression is Downregulated in the Dorsolateral Prefrontal Cortex of Schizophrenics, M. Molnar, et al.
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K) Pathology of Schizophrenia, E. G. Jones
A) Cortical Gene Expression in Depression and Schizophrenia, S. J. Evans
Society for Biological Psychiatry May 15-17,2003
Download Paper B) Anterior Cingulate Gene Expression Differences Found in Bipolar Disorder by Oligonucleotide Microarray Analysis, M. Vawter et al.
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A) A Genome Scan of a Large Costa Rican Family Affected by Schizophrenia  A. Mesén, et al.
World Congress for Psychiatric Genetics (ISPG)  10/4-8/03
Download Paper B) Bipolar and Major Depression Disorder Gene Expression Profiling in Three Brain Regions, M. Vawter, et al
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A) Patterns of Differential Gene Expression in Schizophrenia Overlap in Cortical Regions M. Vawter, et al.  
American Society of Human Genetics 11/4-8/03
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B) Effects of Bipolar Disorder, Major Depression and Suicide on Gene Expression Profiles in Postmortem Brains  H. Tomita, et al.
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A) Gene Expression Discovery in Post-Mortem Human Brain: Bipolar and Major Depressive Disorders, M. Vawter, et al.
Stanley Foundation Meeting November 2003
Download Paper B) Schizophrenia: Patterns of Differential Gene Expression in Cortical Regions, M. Vawter, et al
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A) Stress, Connectivity and Cognitive Decline D. Lyons , et al.  
Amer. Coll. of Neuropsycho-pharmacology 12/7-11/03
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B) Bipolar and Major Depressive Disorders: a Discovery Process Utilizing Microarray Technology W. E. Bunney, et al.
The Molecular Genetics of Schizophrenia K. Cooper-Casey
11th Annual Molecular Psychiatry Meeting 2/8-10/04
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Integrating Functional Genomics for Identification of Candidagte Genes M. Vawter, et al.
Society for Biological Psychiatry 4/29-5/1/04
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A) Bipolar Disorder: A Discovery Process Utilizing Microarray Technology W. E. Bunney , et al.
Collegium Internationale Neuro-Psychopharmacologicum 6/20-24 /04
  B) RNA Expression Studies in Major Depression, S. Watson
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A) Comparisons of RNA Quality Control in Postmorte Brain and Implications to Microarray Analysis of Gene Expression M. Atz, et al.
Society for Neuroscience 10/23-27/04
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B) GABA/Glutamate Signaling Pathways in Bipolar and Major Depressive Disorders J. Li, et al.
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C) Dysregulations of Specific Growth Factor System Gene Expresion in Limbic Structures of Subjects with Major Depressive Disorder S.J. Evans, et al.
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D) Gene Expression Profiling of Squirrel Monkey Brain A.M. Karssen, et al.
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E) Gene Expression Profiles of G-protein Signaling Pathway Related Genes in Postmortem Brains of Mood Disorder Patients H. Tomita, et al.
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F) Effects of Early Postnatal FGF-2 Administration on Neurogensis, Emotionality and Gene Expression in Rats C.A. Turner, et al.
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G) Mitochondrial Related Gene Expression in Affective Disorders in Postmortem Brain M. Vawter, et al.
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H) Strategies for Comparisons of a Postmortem Collection to Subjects in the General Population with Neuropsychiatric Disorders D.M. Walsh, et al.
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I) Tbr-1 mRNA Expression in the Developing Human Cerebral Cortex M. Molnar, et al.
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J) FGF-2 a Possible Predictor for Emotional Reactivity After Environmental Complexity J. Perez, et al.
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Genome Scan of Three Large Extended Costa Rican Pedigrees Affected by Schizophrenia A. Mesen-Fainardi
World Congress of Psychiatric Genetics 10/9-13/04
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SNPS on Chips: COMT SNP Association with Expression! A Word of Caution! M. Burmeister et al.
ACNP 12/12-16/04
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NCAM1 genetic polymorphisms and association with bipolar disorder M. Vawter et al.
ICSR 4/2-6/05 &
Society for Biological Psychiatry 5/19-21/05
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Gene epression profile of G Protein Coupled Receptor related signaling pathways in mood disorder H Tomita et al.
JSBP & JSNP 7/6-8/05
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SNPs on chips: the hidden genetic code in expression arrays M. Burmeister et al.
World Congress of Psychiatric Genetics 10/14-18/05
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Gene expression profile in the brain of rats subjected to chronic unpredictable stress and antidepressant administration: a comparison with human postmortem studies J F Lopez et al.
Albert J. Silverman Research Conference 6/8/05
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Agonal factors, aging, and drug abuse affect mitochondrial gene expression encoded in nucleus and mitochondria in postmortem brain: Implications for neuropsychiatric disorders M. Vawter et al.
Winter Conf on Brain Researc 1/22-28/05
Critical methodological considerations and microarray data that suggests possible non-overlapping unique and overlapping genes shared in both disorders W. Bunney et al.
ICSR 4/2-6/05
Download Paper Cortical gene expression in lithium-treated healthy non-human primate models as windows to mood-stabilizing properties of lithium in bipolar affective disorder P V Choudary et al. Int’l Meeting of the Microarray Gene Expression Data Society 9/11-14/05
Download Paper Long-term changes in hippocampal gene expression after early postnatal FGF2 administration C A Turner, et al. Society for Neuroscience 11/12-16/05
Download Paper Delineating lithium-responsive gene cascades using a non-human primate model P V Choudary et al. Society for Neuroscience 11/12-16/05
Download Paper Sample matching strategies in gene expression studies of brain tissues J Li et al. Society for Neuroscience 11/12-16/05
Download Paper Profiling of transcription-factor activity in rat hippocampus C A Camaano et al. Society for Neuroscience 11/12-16/05
Download Paper Detection of FGF reception 2 splice variants in human post-mortem brain regions and evaluation of differential variant expression in depressed subjects relative to controls S J Evans et al. Society for Neuroscience 11/12-16/05
Download Paper Factors involved in gene expression regulation of g-protein coupled receptors and related signaling pathway genes in mood disorder H Tomita et al.
Society for Neuroscience 11/12-16/05
Download Paper Gene expression profiling of socially stressed squirrel monkey brain A M Karssen, et al. Society for Neuroscience 11/12-16/05
Download Paper Effects of FGF-2 on individual differences in anxiety-like behavior J Perez et al. Society for Neuroscience 11/12-16/05
Download Paper DLX-1 mRNA expression in the dorsolateral prefrontal cortex of schizophrenic patients and controls M. Molnar et al Society for Neuroscience 11/12-16/05
Download Paper Dysregulated Gene Expression In Suicide M.P. Vawter et al ACNP 12/11-15/05
Download Paper Social Stress-Induced Changes in Gene Expression Profiles in Primate Prefrontal Cortex D. Lyons et al Society of Biological Psychiatry 5/18-20/06
     
Download Paper Gene Expression Studies of Postmortem Brain Tissue from Patients with Psychiatric Disorders, I.A.Kerman et al JBSP 9/14-16/06
Download Paper An association study of ninety-three candidate genes in bipolar disorder, D. Absher et al ASHG Meeting 10/9-13/06
Download Paper Association Between Suicide and Body Mass Index among Subjects with Mental Illness, D.M. Walsh et al Society for Neuroscience 10/14-18/06
Download Paper A Role for the Fibroblast Growth Factor System in Cocaine Sensitization, E. Gula et al Society for Neuroscience 10/14-18/06
Download Paper Alterations in the expression of growth factor genes in mood disorders in the dorsal raphe, I.A.kerman et al Society for Neuroscience 10/14-18/06
Download Paper Evaluation of the protection against oxidative stress mediated by mitochondrial dysfunction and the behavioral properties of a derivative of vitamin E, N.Calvo et al Society for Neuroscience 10/14-18/06
Download Paper FGF-2 promotes new cell survival in hippocampus and decreases anxiety-like behavior: differential effects in animals with low novelty-seeking behavior, J. Perez Society for Neuroscience 10/14-18/06
Download Paper Glutamate and fibroblast growth factor signaling pathways in locus coeruleus are altered in major depressive disorder (MDD) but not in bipolar disorder (BPD), R. Bernard Society for Neuroscience 10/14-18/06
Download Paper FGF2: A novel antidepressant?, C. A. Turner Society for Neuroscience 10/14-18/06
Download Paper Design and Analysis of Two-stage Association Studies, M.Boehnke et al WCPG 10/28-11/1/06
Download Paper Bipolar Disorder Candidate Gene Custom SNP panel: Design and Preliminary Results, M.Burmeister et al WCPG 10/28-11/1/06
Download Paper Effect of functional variants on gene expression in human brain, V.Strumba et al ECCB 1/21/-24/07
Download Paper Inheritability of Exon Expression Alterations In Schizophrenia, M.P.Vawter et al ICOSR 3/28-4/1/07
Download Paper Brain Gene Expression Related to Suicide in Mood Disorders, P.A. Sequeira et al Society for Biological Psychiatry 5/17-19/07
Download Paper Cis- and Trans-Regulatory Loci are Implicated with Stress Response in Lymphoblastic Cell Lines, B.Rollins et al Society for Biological Psychiatry 5/17-19/07
Download Paper Mitochondrial Gene Expression in Mood Disorders and Schizophrenia, L.Shao et al Society for Biological Psychiatry 5/17-19/07
Download Paper Neuropharmacogenomic insights into the mechanism of action of lithium in non-human primate model, P V Choudary, et al. IBRO World Congress of Neuroscience 7/12-17/07
Download Paper Determining functional correlation between brain regions at the molecular level, M Dai, et al. ISMB 7/21-25/07
Download Paper Design and analysis of two-stage association studies: application to bipolar 1, M. Boehnke, et al. World Congress on Psychiatric Genetics XV 10/7-11/07
Download Paper Genome-wide association study of bipolar disorder in European Americans, L Scott, et al. World Congress on Psychiatric Genetics XV 10/7-11/07
Download Paper Is a mutation in the neuregulin gene associated with schizophrenia in Costa Rica?, M.P. Vawter, et al. World Congress on Psychiatric Genetics XV 10/7-11/07
Download Paper Genome-wide association study of bipolar disorder in European Americans, J. Li, et al. American Society of Human Genetics 10/23-27/07
Download Paper Combining neurohistology and mRNA expression maps as a guide for anatomical alignments of the mammilary region of the human hypothalamus, A. Medina et al Society for Neuroscience 11/3-7/07
Download Paper Anatomical analysis of gene expression patterns in the paraventricular region of human hypothalamus, D.M. Krolewski, et al. Society for Neuroscience 11/3-7/07
Download Paper Role of fibroblast growth factor (FGF) ligands in the regulation of affective behavior, C.A. Turner, et al. Society for Neuroscience 11/3-7/07
Download Paper Distinct populations of presympathetic-premotor neurons express orexin or melanin-concentrating hormone in the rat lateral hypothalamus, I.A. Kerman, et al Society for Neuroscience 11/3-7/07
Download Paper FGF2 and chronic stress alter exon-specific expression of FGFR2 and FGFRE, J.S. Liu, et al. Society for Neuroscience 11/3-7/07
Download Paper Phosphotyrosine profiling in brain tissue: a methodology to study the impact of growth factors signaling, C. A. Caamano Society for Neuroscience 11/3-7/07
Download Paper Gastrin releasing peptide (GRP) and glucocorticoid-induced receptor (GIR) mRNA expression are upregulated in locus coeruleus of bipolar disorder (BPD) but not in major depressive disorder (MDD) patients, R. Bernard Society for Neuroscience 11/3-7/07
 

 
 

 

 
 
Pritzker Consortium, 2007